Over the past year we have initiated 11 new research projects and been responsible for 88 peer-reviewed publications of primary research, as well as a further 31 publications of chapters, reviews and commentaries of expert opinion. As a wider research unit, we continue to work towards improving the recognition of epilepsy as a healthcare priority in every part of the world.
Our work is driven by a commitment to improving the lives of children and young people with epilepsy and associated conditions.
Over the past year, we’ve made significant progress:
- We initiated 11 new research projects and contributed to 88 peer-reviewed publications, plus 31 expert reviews and chapters.
- We hosted our 7th Paediatric Epilepsy Research Retreat, bringing together global experts to share insights and shape future research.
- Our research is guided by six strategic goals, including understanding causes, improving treatment, and supporting education and family wellbeing.
Key Projects and Achievements
- EPIPEG: We identified new genes linked to early onset epileptic encephalopathy, helping tailor treatments sooner.
- Landau Kleffner Syndrome: We found GRIN2A mutations in 12% of screened patients, aiding earlier diagnosis and intervention.
- Dravet Syndrome Studies: We explored links between heart rhythm and SUDEP, aiming to improve monitoring and care.
- Ketogenic Diet Trials: We tested its effectiveness in infants and developed new MCT-based products to improve tolerability.
- Cannabidiol Research: Our studies showed seizure reduction in severe epilepsy cases, supporting its use as add-on therapy.
- ABLE Tool: We developed a screening tool for teachers and parents to identify learning and behavioural needs in children with epilepsy.
- WINS Project: We’re gathering views from children, parents and teachers to create school guidelines for epilepsy support.
Our Collaborative Approach
- We work closely with UCL GOS Institute of Child Health and Great Ormond Street Hospital, forming a unique multidisciplinary team.
- Our network spans over 30 universities and research centres worldwide.
- We’ve supervised over 40 PhD projects, nurturing the next generation of epilepsy researchers.
Looking Ahead
- We’re committed to translating research into practical outcomes for young people and families.
- We continue to campaign for joined-up services, better education support, and personalised care.
- Our work is made possible by generous support from charities, foundations, and individuals.
We believe that every child with epilepsy deserves the best chance at a full and happy life. Through research, collaboration and advocacy, we’re working to make that vision a reality.
