Develop robust and rapid simultaneous EEG-fMRI measurements
The fast without the spurious: developing a system for robust and rapid simultaneous EEG-fMRI measurements
Aim
To develop more advanced EEG-fMRI scans that may better detect brain areas active at the start of seizures. To do this we are trying new motion-correction technology that tells the scanner where the head is using a camera and a marker attached to a dental retainer and updates the scanner accordingly.
What this means
We are trying to understand exactly what parts of a patient's brain are active during a seizure and whether or not they may be contributing to seizure activity. This study will help us to better identify any abnormalities causing the seizures and, we hope, lead to more targeted treatment earlier.
Update
The project is now coming to a close and we are writing up both another advancement to improve EEG quality during subject movement and our assessment of more rapid fMRI sequences. We have been collecting a small case series so far to test our new EEG-fMRI acquisition and hope to capture the onset of seizures.
Investigators
Amy McDowell, Danilo Maziero, David Carmichael, Helen Cross, Kelly St Pier, Nikolaus Weiskopf
Further information
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Young Epilepsy is the operating name of The National Centre for Young People with Epilepsy (NCYPE).