Better futures for young lives with epilepsy and associated conditions
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Epilepsy emergency medication

A seizure is not normally a medical emergency and the vast majority of seizures stop by themselves without the need for any treatment. However sometimes a medical emergency known as status epilepticus can occur.

Status epilepticus

This is defined as any seizure involving unconsciousness lasting for 30 minutes or longer; or repeated seizures lasting for 30 minutes in total from which the person does not regain consciousness between each seizure.

Although any type of seizure may develop into status epilepticus, generalised tonic clonic seizures progressing into status epilepticus are the most serious.

The longer a seizure continues, the harder it is to stop. So best practice is to treat a generalised tonic clonic seizure with emergency medication after five minutes. This is also known as rescue medication.

Epilepsy emergency medication may be prescribed if a child has previously experienced a seizure that has lasted for five minutes or more. An action plan should be agreed with the doctor so that you know what to do in an emergency situation. This should be shared with the child’s school and staff who will administer the medication need to be trained to do so.

Emergency drugs have an anticonvulsant effect and can stop seizures. Midazolam and Diazepam are the two most commonly used.


Midazolam is a liquid rescue medication that is released into the mouth between the cheek and the gums (known as the buccal cavity). The advantages of Midazolam are that it does not cause prolonged drowsiness (normally only 24 hours) and it is very easy to administer during a seizure.

Emergency Medication Training Pack

Very occasionally Midazolam can cause breathing difficulties. If this happens, call 999.

Emergency medication training pack - buccal Midazolam

Our free training tool for the administration of buccal Midazolam helps parents know what to do in an emergency. It is also a useful revision tool for education and care professionals who have already received training.

Emergency Medication Training Pack


Diazepam is a rescue medication that is given via the rectal route (into the bottom).

Information on how to administer it is included in the packaging but a nurse will usually talk it through with parents. Any school staff who may need to administer medication will need training.

Rectal Diazepam may be difficult to administer if the child is in a wheelchair, or getting them in a suitable position to give the medication during a seizure.

Other problems include if the child is constipated or their bowels open when it is given, which can mean that an incorrect dose is administered.

The child will be drowsy after receiving the medication and this can continue for 12 hours or more. Very rarely breathing difficulties may occur, but if this does happen, call an ambulance immediately.

This video shows how epilepsy can affect a family as well as how to administer Buccal Midazolam.

Helpline: 01342 831342 (Mon-Fri, 9am-3pm)
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Star Fact!

The numbers of young people who are 25 years and under with epilepsy is around 112,000.

Cyber EssentialsFundraising RegulatorYoung Epilepsy is the operating name of The National Centre for Young People with Epilepsy (NCYPE).
Registered Charity number 311877 (England and Wales)

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